![]() C.Protostomes are lower invertebrate species in which the mouth develops before the anus during embryo development. The Big Six High Table 6.2 Experimental advantages and disadvantages of six model organisms. There are also some more objective practical considerations that govern the selection of organisms for particular purposes, which are summarized in the table in the next slide.True that sometimes individual scientists choose their organism just because they like looking at them and working with them.These six model organisms have each been selected because they have some particular experimental advantages for developmental biology research. Selection of organisms for particular purposes are in Table 6.2 Selected because they have an experimental advantage for developmental biology research.Deuterostomes -The first opening, the blastopore, becomes the anus, they have radial cleavage, regulative development and blastocoel that forms pouches growing and separating from the digestive tract.They have spiral cleavage, mosaic development and a blastocoel forms by hollowing out a ball of cells Protostomes - The first opening in the embryo, the blastopore becomes the mouth.However, the evolutionary distance between them is sufficiently large to make it likely that any developmental features possessed by all 6 is shared by the entire animal kingdom.Note on the previous slide that the big 6 they do not provide very good coverage of the animal kingdoms, as there are just 2 invertebrates and 4 vertebrates. ![]() In this chapter we will explain why research activity has focused down onto a small number of species, with some comparative indications of their strengths and weaknesses.
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